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Does Retin A make skin worse before better? Yes, the tretinoin cream may make your acne worse before it gets better. In patients with acne, new cells replace the cells of existing pimples, and the rapid turnover of cells prevents new pimples from forming. In the same way, tretinoin can reduce some wrinkles, areas of darkened skin, and rough areas of skin. Does tretinoin cream 0.05 work for acne? Tretinoin can also be used to decrease the appearance of acne scarring. Since tretinoin speeds up cell turnover on your skin, it can encourage new cell growth at the site of scarring. Tretinoin in several forms has been tested successfully as an effective way to treat acne scars. How long does tretinoin take to work on acne? Tretinoin Takes Three to Six Months to Produce Results. In general, it takes three to six months to see results from tretinoin. This is supported by several studies, all of which showed a significant improvement in skin quality and reduction in acne after 12 weeks of using tretinoin.
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