Is sepsis usually fatal? Sepsis is a complication of infection that leads to organ failure. More than one million patients are hospitalized for sepsis each year. People with chronic medical conditions, such as neurological disease, cancer, chronic lung disease and kidney disease, are at particular risk for developing sepsis. And it is fatal. Can C difficile cause death? Approximately 29,000 patients died within 30 days of the initial diagnosis of C. difficile. More than 80 percent of the deaths associated with C. difficile occurred among Americans aged 65 years or older. C. difficile causes an inflammation of the colon and deadly diarrhea.
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